Immunology: What do read before AIIMS PG and NEET PG?

Why immunology is a good read before AIIMS PG?

Immunology is  rapidly advancing area of medicine and hence one of the most important clinical and preclinical topic for medical PG entrance exam preparation. Both immunology and rheumatology have been examiners favourites in 2014-16 for AIIMS PG, DNB and AIPGMEE. The repeated questions are numerous and the new MCQs are often hard to guess. This article is about the important areas that needs to be covered both MCQs and reading standard textbooks for your NEET PG 2017 preparation.

The underlined areas are must-read before exam. You may also use the underlined words as keywords on platinum access to cover the key MCQs from the area. Some of the must-read important topics are B lymphocytes, T lymphocytes, Distinguishing features of T cells and B cells, Cytotoxic T Cell and B cell, Cytotoxic T cells, Helper T cells, Types of Immunity, Complement Pathways and Immunoglobulin Isotypes. Not to forget, Hypersensitivity Reaction, a many times repeated high yielding area.

AIPGMEE MCQ Example 1: Which of the following antibody mediates Type I hypersensitivity reaction?
A. IgA

B. IgG
C. IgM
D. IgE


Read before AIIMS PG

Prepare and immunology read list for NEET PG:

It is important that you have read the following areas at least once for your medical PG preparation 2016-17, preferably from the new Harrison’s Principles of Internal Medicine, 19e. The key areas for NEET PG, DNB and AIIMS PG are Types of Grafts, Graft rejection reaction, Interferons, Tumor Necrosis Factor, Important Cytokines, Colony stimulating Factors, Natural Killer cells, and Major Histocompatibility complex.

Clinical immunology MCQs can be from Primary Immunodeficiency diseases like T cell disorder, B-cell disorder, Combined B and T cell disorders and Neutrophilic and Phagocytic disorders. ANCA Associated disease which are commonly asked for NBE exams (NEET PG, AIPGMEE & DNB)

AIIMS PG MCQ Example 2: A 52 year old male presents with sinus pain and drainage, bloody nasal discharge, and nasal mucosal ulceration. On laboratory examination, the man is found to have proteinuria, hematuria, and red blood cell casts. A biopsy of the upper airway tissue reveals granulomatous inflammation with necrosis. Renal biopsy confirms the existence of glomerulonephritis. Blood tests show the presence of antineutrophil cytoplasmic antibodies (c-ANCA). What is the most likely diagnosis?

A. Allergic angiitis
B. Goodpasture’s syndrome
C. Non-infectious granulomatous disease
D. Wegener’s granulomatosis


You should definitely expect questions from Complement deficiency disorders And complement pathway.

AIPGMEE MCQ Latest Example 3: Which of the following complement act as a chemoattractant of neutrophils? 
A. C3a
B. C3b
C. C5a


Therapeutic antibodies/ Immunosuppressant Drugs are important advancing topics. Read about Infliximab, trastuzumab, omalizumab, Rituximab and Adalimumab. You may also expect questions from Immunoglobulins Isotypes

DNB MCQ Example 4: Which of the following immunoglobulin crosses placenta readily and can activate complements? 
A. IgG
B. IgA
C. IgM
D. IgD

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The references for the above questions were from the following:

Q1) Brooks GF, Carroll KC, Butel JS, Morse SA, Mietzner TA. Chapter 8. Immunology. In: Brooks GF, Carroll KC, Butel JS, Morse SA, Mietzner TA.eds. Jawetz, Melnick, & Adelberg’s Medical Microbiology, 26e.

Q2) Stone J.H. (2013). Chapter 32. Granulomatosis with Polyangiitis (Wegener Granulomatosis). In J.B. Imboden, D.B. Hellmann, J.H. Stone (Eds), CURRENT Diagnosis & Treatment: Rheumatology, 3e.

Q3) Levinson W. (2012). Chapter 63. Complement. In W. Levinson (Ed), Review of Medical Microbiology & Immunology, 12e.

Q4) Ref: Levinson W. (2012). Chapter 59. Antibodies. In W. Levinson (Ed), Review of Medical Microbiology & Immunology, 12e.

This article gives you a comprehensive read list for NEET PG on the high yielding topic immunology. The topics here are highly recommended read before AIIMS PG 2016-17. This article is about the important areas that needs to be covered both MCQs and reading standard textbooks for your NEET PG 2017 preparation. A good NEET PG result can be expected with organised learning.

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