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DAILY FREE MCQ CHALLENGE for Medical PG Preparation
Question
Which among the following is the highly sedative H1 antihistaminic?
a) Fexofenadine
b) Diphenhydramine
c) Chlorpheniramine
d) Cyclizine
TIPSImportant Question from
KARNATAKA 2011
See Answer Here
b) Diphenhydramine
See Explanation Here
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H1 ANTIHISTAMINIC
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Highly sedative
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Diphenhydramine, Dimenhydrinate, Promethazine, Hydroxyzine
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Moderately sedative
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Pheniramine, Cyproheptadine, Meclizine, Buclizine, Cinnarizine
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Mild sedative
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Chlorpheniramine, Dexchlorpheniramine, Triprolidine, Clemastine
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Second generation
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Fexofenadine, Loratadine, Desloratadine, Cetirizine, Levocetirizine, Azelastine, Mizolastine, Ebastine, Rupatadine
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Terfenadine and astemizole are the earliest second generation H1 antihistamines that are now banned. Cyclizine, buclizine, dimethindene, mebhydrolin are conventional antihistamines that have become unavailable.
References
Page no: 164, Chapter: Histamine and Antihistaminic; KD Tripathi-Essentials of Medical Pharmacology/ 7e.
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