DAILY FREE MCQ CHALLENGE for Medical PG Preparation
Which amino acids Deamination take place in liver?
A. Glutamine B. Glycin C. Alanine D. Aspartic acid
TIPSImportant Question from JIPMER 2010
See Answer Here
See Explanation Here
Removal of the amino groups of amino acids is referred to as Deamination. In the course of Deamination, Desulphurization and transamination with glutamine or Asparagine, ammonia is produced as a necessary evil.
Ammonia, derived mainly from the amino nitrogen of amino acids , is highly toxic. Tissues therefore convert ammonia to the amide nitrogen of the nontoxic amino acid glutamine.
Subsequent Deamination of glutamine in the liver releases ammonia, which is then converted to urea, which is not toxic.
CChapter 28. Catabolism of Proteins & of Amino Acid Nitrogen. In: Harper’s Illustrated Biochemistry, 29e.; Textbook of Medical Biochemistry By S. Ramakrishnan/ 3e.
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