FREE DNB MCQ on 27 Sep 2016

DNB
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 DAILY FREE MCQ CHALLENGE for Medical PG Preparation

Question
Which among the following is due to Wolf- Hirschhorn Syndrome?

A. 18q syndrome
B. 4p
C. 5p
D. Deletion of 13q

TIPSImportant Question from DNB 2015

B. 4p

Wolf-Hirschhorn Syndrome

  • Also known as 4p− (deletion of 4p16), this syndrome is characterized by microcephaly and unusual development of the nose and orbits that produces an appearance suggesting an ancient Greek warrior’s helmet.
  • Other anomalies commonly seen include cleft lip and palate and cardiac and renal defects.
  • Seizure disorders are common, and the majority of patients have severe intellectual disability.

baby-with-cleft-lip

 

Genetics & Dysmorphology. In: Hay WW, Jr., Levin MJ, Deterding RR, Abzug MJ. eds. CURRENT Diagnosis & Treatment: Pediatrics, 22e. Reference link

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