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DAILY FREE MCQ CHALLENGE for Medical PG Preparation
Which among the following is true about hypercapnia?
A. Elevated PaCO2
B. Deficiency of HCO3
TIPSImportant Question from AIIMS 2013
Answer: A. Elevated PaCO2
Hypercapnia is exclusively caused by alveolar hypoventilation and is defined as a PaCO2 >45 mm Hg. Alveolar hypoventilation has many causes, including rapid shallow breathing, small tidal volumes, underventilation of the lung, or reduced respiratory drive.
Retention of larger amounts produces such symptoms as confusion, diminished sensory acuity and, eventually, coma with respiratory depression and death due to depression of the central nervous system. In patients with these symptoms, the Pco2 is markedly elevated and severe respiratory acidosis is present. Large amounts of HCO3− are excreted, but more HCO3− is reabsorbed, raising the plasma HCO3− and partially compensating for the acidosis.
Gas Transport & pH. In: Barrett KE, Barman SM, Boitano S, Brooks HL. eds. Ganong’s Review of Medical Physiology, 25e. Reference link
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